Low-substituted hydroxypropyl cellulose is a non-ionic, water insoluble functional disintegrant. It can improve stability for oxygen and water sensitive APIs and has an anti-capping effect due to the fibrous nature of the particle.
L-HPC is mainly used as a tablet disintegrating agent, to improve tablet disintegration of tablets can accelerate the collapse of the poor after the collapse and disintegration of the fineness of dispersion, thereby improving bioavailability, while the product with the bonding effect on the shape of the drugs can also be easily formed to promote and improve tablet hardness. it Can be used for wet granulation can also be used for dry particles, can also be added as a binder used in starch, can receive increased tablet hardness and improve the effect of tablet disintegration.
Dosage 2-5% of the product.
L-HPC is mainly used as a tablet disintegrating agent, to improve tablet disintegration of tablets can accelerate the collapse of the poor after the collapse and disintegration of the fineness of dispersion, thereby improving bioavailability, while the product with the bonding effect on the shape of the drugs can also be easily formed to promote and improve tablet hardness. it Can be used for wet granulation can also be used for dry particles, can also be added as a binder used in starch, can receive increased tablet hardness and improve the effect of tablet disintegration.
Dosage 2-5% of the product.
| Items | USP(ZLH-22) | USP(ZLH-21) | CP |
|---|---|---|---|
| Hydroxypropoxy assay,% | 7.0 - 9.9 | 10.0 - 12.9 | 7.0 - 16.0 |
| Loss on drying,% | <5.0 | <8.0 | |
| Heavy metal,ppm | 10 | 20 | |
| Residue on ignition,% | <0.5 | <1.0 | |
| Chloride,% | <0.36 | <0.2 | |
| Arsenic, ppm | <3 | ||
